Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28527900 | 0.85 | BCL2 (0.51) | BCL2MCL1GABRA1GABRB1AKR1C3 | |
| SCHEMBL10007412 | 0.85 | ALDH1A1 (0.59) | AKR1C3ALDH1A1KMT2ALMNAGAA | |
| SCHEMBL1122739 | 0.80 | BCL2 (0.64) | BCL2MCL1GABRA1GABRB1AKR1C3 | |
| SCHEMBL2943909 | 0.80 | ACE2 (0.50) | GABRA1GABRB1ALDH1A1KMT2ALMNA | |
| SCHEMBL27876135 | 0.80 | AKR1C3 (0.63) | AKR1C3ALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL30007458 | 0.78 | ALDH1A1 (0.50) | AKR1C3ALDH1A1KMT2ALMNAGAA | |
| SCHEMBL12792099 | 0.78 | AKR1C3 (0.67) | AKR1C3ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL109891 | 0.78 | ALDH1A1 (0.50) | AKR1C3ALDH1A1KMT2ALMNAGAA | |
| SCHEMBL3879139 | 0.77 | GAA (0.55) | BCL2MCL1GABRA1GABRB1AKR1C3 | |
| SCHEMBL28424851 | 0.76 | BCL2 (0.59) | BCL2MCL1GABRA1GABRB1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104853753-A | Formulations comprising idebenone, n-acetyl-s-farnesyl-l-cysteine and ergothioneine and uses thereof | ARDEN ELIZABETH INC | 2015-08-19 | — | — | CN | disclosed |