⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171873 | 0.88 | ALDH1A1 (0.40) | — | |
| SCHEMBL11078598 | 0.86 | TLR8 (0.41) | — | |
| SCHEMBL2881981 | 0.82 | — | — | |
| SCHEMBL14112922 | 0.78 | MEN1 (0.40) | — | |
| Trichlorethanol SCHEMBL11368078 | 0.76 | ALDH1A1 (0.33) | — | |
| Nitroethane SCHEMBL11374954 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL10838868 | 0.75 | ALDH1A1 (0.35) | — | |
| SCHEMBL11371325 | 0.74 | TSHR (0.38) | — | |
| SCHEMBL19288770 | 0.74 | — | — | |
| SCHEMBL5280196 | 0.74 | HSD11B1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116162926-A | Copper surface antioxidant composition and preparation method thereof | 深圳市正天伟科技有限公司 | 2023-05-26 | — | — | CN | disclosed |
| US-20210087167-A1 | ASK1 INHIBITOR COMPOUNDS AND USES THEREOF | Seal Rock Therapeutics, Inc. | 2021-03-25 | — | — | US | disclosed |
| US-8338460-B2 | 3-({4-[2-(dimethylamino)ethoxy]phenyl}thio)-N-(3-methyl-1,2,4-thiadiazol-5-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)thio]pyridine-2-carboxamide; glucokinase activator; antidiabetic, obesity | MSD K. K. (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20100261699-A1 | N-PYRAZOLE-2-PYRIDINE CARBOXAMIDE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. | 2010-10-14 | — | — | US | disclosed |
| EP-2236507-A1 | N-PYRAZOLE-2-PYRIDINECARBOXAMIDE DERIVATIVE | Banyu Pharmaceutical Co., Ltd. (JP) | 2010-10-06 | — | — | EP | disclosed |
| EP-2077266-A1 | 2-PYRIDINECARBOXAMIDE DERIVATIVE HAVING GK-ACTIVATING ACTIVITY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-07-08 | — | — | EP | disclosed |
| US-20080090799-A1 | 2-PYRIDINECARBOXAMIDE DERIVATIVE HAVING GK-ACTIVATING EFFECT | MSD K.K. (JP) | 2008-04-17 | — | — | US | disclosed |