Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5283248 | 0.88 | ALDH1A1 (0.40) | ADORA2AALDH1A1SMN1; SMN2PDE4APDE4B | |
| SCHEMBL5279872 | 0.85 | ADORA2A (0.33) | HSD11B1ADORA2AADORA2BADORA1PDE4A | |
| SCHEMBL3459979 | 0.83 | ADORA2A (0.32) | ADORA2AADORA2BADORA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5656633 | 0.83 | ADORA2A (0.32) | ADORA2AADORA2BADORA1 | |
| SCHEMBL5275734 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL5655082 | 0.82 | ADORA2A (0.31) | ADORA2AADORA2BADORA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5279788 | 0.82 | ALDH1A1 (0.35) | HSD11B1ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL5273283 | 0.80 | ADORA2A (0.30) | ADORA2AADORA2BADORA1 | |
| SCHEMBL16509680 | 0.80 | MEN1 (0.39) | ADORA2AADORA2BALDH1A1SMN1; SMN2PDE4A | |
| SCHEMBL5274958 | 0.80 | CYP1A2 (0.35) | ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |