Isobutylbenzene

Isobutylbenzene

SCHEMBL28820972

CC(C)Cc1ccccc1.O=COCCS(=O)(=O)c1ccccc1

nearest known ligand 0.49

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
PSIP1 O75475 1/20 0.40
ALDH1A1 P00352 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MAPT P10636 1/20 0.38
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
BACE1 P56817 2/20 0.36
CTSD P07339 1/20 0.36
HSD11B1 P28845 1/20 0.36
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isobutylbenzene SCHEMBL28023631 0.93 HDAC1 (0.38) MEN1KMT2ATAAR1PSIP1ALDH1A1
Isobutylbenzene SCHEMBL28023634 0.87 TAAR1 (0.41) MEN1KMT2ATAAR1PSIP1ALDH1A1
SCHEMBL28052 0.84 PSIP1 (0.48) MEN1KMT2APSIP1ALDH1A1MAPT
Isobutylbenzene SCHEMBL28023629 0.82 MMP1 (0.39) MEN1KMT2ATAAR1ALDH1A1CYP1A2
Butylbenzyl SCHEMBL28023624 0.80 CNR2 (0.44) MEN1KMT2APSIP1ALDH1A1CA2
Isobutylbenzene SCHEMBL28023640 0.79 TAAR1 (0.39) MEN1KMT2ATAAR1ALDH1A1CYP1A2
SCHEMBL31135379 0.77 HDAC1 (0.46) KMT2APSIP1ALDH1A1CYP1A2CYP2C9
Isobutylbenzene SCHEMBL27746774 0.77 TAAR1 (0.47) MEN1KMT2ATAAR1CYP2C9LMNA
Isobutylbenzene SCHEMBL28023015 0.76 MMP1 (0.41) MEN1KMT2ATAAR1ALDH1A1CYP1A2
Isobutylbenzene SCHEMBL27821325 0.74 TAAR1 (0.52) MEN1KMT2ATAAR1CYP2C9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103509135-B Olefin polymerization catalyst component, preparation method and application thereof CHINA PETROLEUM & CHEMICAL 2015-07-22 CN disclosed