Isobutylbenzene

Isobutylbenzene

SCHEMBL28023015

CC(C)Cc1ccccc1.CCC(COC=O)S(=O)(=O)c1ccccc1

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 9/20 0.41
MMP13 P45452 6/20 0.41
MMP2 P08253 4/20 0.40
MMP3 P08254 4/20 0.40
PDE4A P27815 3/20 0.40
PDE4B Q07343 3/20 0.40
PDE4C Q08493 3/20 0.40
PDE4D Q08499 3/20 0.40
MMP7 P09237 3/20 0.36
MMP12 P39900 3/20 0.36
ACE P12821 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
ALDH1A1 P00352 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
MMP9 P14780 1/20 0.34
TRPA1 O75762 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isobutylbenzene SCHEMBL28023640 0.85 TAAR1 (0.39) MMP1MMP13MMP2MMP3PDE4A
Butylbenzyl SCHEMBL28023013 0.84 MMP1 (0.41) MMP1MMP13MMP2MMP3PDE4A
Isobutylbenzene SCHEMBL28023629 0.78 MMP1 (0.39) MMP1MMP13MMP2MMP3PDE4A
Isobutylbenzene SCHEMBL28023634 0.77 TAAR1 (0.41) MEN1KMT2ATAAR1ALDH1A1CYP1A2
Isobutylbenzene SCHEMBL28820972 0.76 MEN1 (0.40) MEN1KMT2ATAAR1ALDH1A1CYP1A2
Isobutylbenzene SCHEMBL27746774 0.76 TAAR1 (0.47) MEN1KMT2ATAAR1CYP2C9TRPA1
Isobutylbenzene SCHEMBL28023631 0.73 HDAC1 (0.38) MMP1MMP13MMP3MEN1KMT2A
Butylbenzyl SCHEMBL28023730 0.72 ALDH1A1 (0.41) MMP1MMP13MMP2MMP3PDE4A
SCHEMBL2443658 0.72 PSIP1 (0.54) MMP1MMP13MMP7MMP12ACE
SCHEMBL98648 0.71 TAAR1 (0.49) MEN1KMT2ATAAR1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103509135-B Olefin polymerization catalyst component, preparation method and application thereof CHINA PETROLEUM & CHEMICAL 2015-07-22 CN disclosed