Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 9/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | IDH2 | P48735 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16804753 | 0.89 | MTOR (0.43) | CTSCTP53MAPTSMN1; SMN2MTOR | |
| SCHEMBL16086165 | 0.88 | IDH2 (0.44) | CTSCTP53MAPTSMN1; SMN2MTOR | |
| SCHEMBL14978436 | 0.83 | CTSC (0.44) | CTSCTP53MAPTSMN1; SMN2MTOR | |
| SCHEMBL27930761 | 0.83 | MTOR (0.39) | CTSCTP53MAPTSMN1; SMN2MTOR | |
| SCHEMBL15615876 | 0.80 | MPO (0.51) | CTSCTP53MAPTSMN1; SMN2MTOR | |
| SCHEMBL15615888 | 0.78 | LMNA (0.53) | TP53MAPTMTORIDH2 | |
| SCHEMBL15615882 | 0.77 | MAPT (0.52) | TP53MAPTSMN1; SMN2 | |
| SCHEMBL15615969 | 0.72 | CNR2 (0.58) | APP | |
| SCHEMBL2163621 | 0.71 | PIM1 (0.50) | CTSCTP53MAPTSMN1; SMN2IDH2 | |
| SCHEMBL27951117 | 0.68 | MELK (0.32) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884456-A | Pi3k and/or mtor inhibitor | KBP BIOSCIENCES CO LTD | 2015-09-02 | — | — | CN | disclosed |