Orthocresol

Orthocresol

SCHEMBL28822341

CC(N)=O.Cc1ccccc1O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
HPGD P15428 4/20 0.54
HSD17B10 Q99714 4/20 0.54
KDM4E B2RXH2 3/20 0.54
MAPT P10636 3/20 0.54
TSHR P16473 3/20 0.54
TRPA1 O75762 2/20 0.46
ATM Q13315 1/20 0.46
THRB P10828 1/20 0.44
LMNA P02545 4/20 0.44
HTT P42858 2/20 0.44
MAPK1 P28482 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
MEN1 O00255 1/20 0.42
ESR1 P03372 1/20 0.42
KMT2A Q03164 1/20 0.42
ESR2 Q92731 1/20 0.42
POLB P06746 2/20 0.41
NPC1 O15118 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orthocresol SCHEMBL10349755 0.93 ALDH1A1 (0.56) ALDH1A1HPGDHSD17B10KDM4EMAPT
Orthocresol SCHEMBL29233113 0.91 KDM4E (0.54) ALDH1A1HPGDHSD17B10KDM4EMAPT
Orthocresol SCHEMBL18725587 0.90 TRPA1 (0.50) ALDH1A1HPGDHSD17B10KDM4EMAPT
Orthocresol SCHEMBL27537729 0.88 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10KDM4EMAPT
Orthocresol SCHEMBL4080689 0.88 TRPA1 (0.48) ALDH1A1HPGDHSD17B10KDM4EMAPT
Orthocresol SCHEMBL28747710 0.85 TRPA1 (0.50) ALDH1A1HPGDHSD17B10KDM4EMAPT
Orthocresol SCHEMBL6566573 0.85 TRPA1 (0.50) ALDH1A1HPGDHSD17B10KDM4EMAPT
Orthocresol SCHEMBL10495968 0.85 TRPA1 (0.55) ALDH1A1HPGDHSD17B10KDM4EMAPT
Orthocresol SCHEMBL27885292 0.85 TRPA1 (0.55) ALDH1A1HPGDHSD17B10KDM4EMAPT
O-Xylene SCHEMBL8469340 0.85 TSHR (0.59) ALDH1A1HPGDHSD17B10KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105061232-A Preparation method for red base B XIANGSHUI HENRYDA TECH CHEMICAL CO LTD 2015-11-18 CN disclosed