Orthocresol

Orthocresol

SCHEMBL29233113

Cc1ccccc1O.NC(=O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.54
ALDH1A1 P00352 5/20 0.54
HPGD P15428 5/20 0.54
HSD17B10 Q99714 5/20 0.54
MAPT P10636 3/20 0.54
TSHR P16473 2/20 0.54
TRPA1 O75762 2/20 0.46
ATM Q13315 1/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
CA12 O43570 2/20 0.44
CA2 P00918 2/20 0.44
CA4 P22748 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CA14 Q9ULX7 2/20 0.44
CA1 P00915 1/20 0.44
HMGB1 P09429 1/20 0.44
CA6 P23280 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orthocresol SCHEMBL10349755 0.93 ALDH1A1 (0.56) KDM4EALDH1A1HPGDHSD17B10MAPT
Orthocresol SCHEMBL28822341 0.91 ALDH1A1 (0.54) KDM4EALDH1A1HPGDHSD17B10MAPT
Orthocresol SCHEMBL6566573 0.90 TRPA1 (0.50) KDM4EALDH1A1HPGDHSD17B10MAPT
Orthocresol SCHEMBL28747710 0.90 TRPA1 (0.50) KDM4EALDH1A1HPGDHSD17B10MAPT
Orthocresol SCHEMBL27537729 0.88 ALDH1A1 (0.52) KDM4EALDH1A1HPGDHSD17B10MAPT
Orthocresol SCHEMBL14856303 0.88 TRPA1 (0.48) KDM4EALDH1A1HPGDHSD17B10MAPT
Orthocresol SCHEMBL4080689 0.88 TRPA1 (0.48) KDM4EALDH1A1HPGDHSD17B10MAPT
Orthocresol SCHEMBL3862455 0.87 TRPA1 (0.57) KDM4EALDH1A1HPGDHSD17B10MAPT
Orthocresol SCHEMBL9648880 0.86 TRPA1 (0.46) KDM4EALDH1A1HPGDHSD17B10MAPT
Orthocresol SCHEMBL27415541 0.86 TRPA1 (0.46) KDM4EALDH1A1HPGDHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118215651-A Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition 旭化成株式会社 2024-06-18 CN disclosed