Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27748629 | 0.85 | PNMT (0.39) | PNMTSMN1; SMN2LMNATAAR1L3MBTL1 | |
| SCHEMBL778836 | 0.84 | L3MBTL1 (0.48) | SMN1; SMN2LMNAL3MBTL1HTTKDM4E | |
| SCHEMBL27537851 | 0.81 | L3MBTL1 (0.39) | SMN1; SMN2LMNAL3MBTL1HTTMAPT | |
| SCHEMBL27769274 | 0.81 | PNMT (0.47) | PNMTSMN1; SMN2LMNATAAR1L3MBTL1 | |
| SCHEMBL27650151 | 0.81 | INPPL1 (0.52) | PNMTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| Phosphoric Acid SCHEMBL28106182 | 0.79 | INPPL1 (0.50) | PNMTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL27770071 | 0.79 | PNMT (0.37) | PNMTSMN1; SMN2LMNATAAR1L3MBTL1 | |
| SCHEMBL27881642 | 0.79 | CA1 (0.40) | PNMTL3MBTL1MAPTALDH1A1GAA | |
| SCHEMBL779406 | 0.77 | KDM4E (0.45) | LMNAKDM4EALDH1A1GAA | |
| SCHEMBL27769863 | 0.75 | CA2 (0.45) | PNMTSMN1; SMN2LMNAL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926871-A | O,O-dialkyl-alpha-[3-bromo-1-(3-chloro-2-pyridyl)-1H-pyrazole-5-formyl]alkyl methylphosphonate derivative as well as preparation method and application thereof | XIAN MODERN CHEMISTRY RES INST | 2015-09-23 | — | — | CN | disclosed |