Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 5/20 | 0.48 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.47 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2211969 | 0.95 | FYN (0.44) | FYNPIP4K2APIP4K2BCYP17A1CYP11B1 | |
| SCHEMBL2882567 | 0.95 | RAD52 (0.47) | FYNPIP4K2APIP4K2BCYP17A1CYP11B1 | |
| SCHEMBL2214072 | 0.88 | FYN (0.50) | FYNRAD52ALDH1A1MAPTMEN1 | |
| SCHEMBL2882015 | 0.82 | CYP17A1 (0.47) | FYNCYP17A1CYP11B1CYP11B2RAD52 | |
| SCHEMBL2214081 | 0.82 | SCD (0.42) | CA2ALDH1A1MAPTMEN1HPGD | |
| SCHEMBL2882294 | 0.81 | FYN (0.48) | FYNPIP4K2APIP4K2BCYP17A1CYP11B1 | |
| SCHEMBL2209540 | 0.80 | BPTF (0.36) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL2214323 | 0.79 | ALDH1A1 (0.41) | CA2ALDH1A1MAPTMEN1HPGD | |
| SCHEMBL2880155 | 0.79 | PLK1 (0.43) | FYNPIP4K2APIP4K2BCYP17A1CYP11B1 | |
| SCHEMBL2880093 | 0.77 | RAD52 (0.48) | FYNCYP17A1CYP11B1CYP11B2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745446-B2 | Pyrazolo[1,5-c]pyrimidines | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-29 | — | — | US | disclosed |
| US-20070254046-A1 | Novel Pyrazolopyrimidines | ALTANA PHARMA AG (DE) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254046-A1 | Novel Pyrazolopyrimidines | MCL1, RARS2, CDK4 | FYN 3232/4885PIP4K2A 1325/4885PIP4K2B 1081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.