Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288227 | 0.83 | HSP90AA1 (1.00) | HSP90AA1TSHRLMNAACHEALDH1A1 | |
| SCHEMBL11356136 | 0.83 | HSP90AA1 (0.77) | HSP90AA1TSHRLMNAACHEALDH1A1 | |
| SCHEMBL31405188 | 0.83 | HSP90AA1 (0.77) | HSP90AA1TSHRLMNAACHEALDH1A1 | |
| SCHEMBL20347051 | 0.83 | HSP90AA1 (0.77) | HSP90AA1TSHRLMNAACHEALDH1A1 | |
| SCHEMBL31482901 | 0.83 | HSP90AA1 (1.00) | HSP90AA1TSHRLMNAACHEALDH1A1 | |
| SCHEMBL30468119 | 0.83 | HSP90AA1 (1.00) | HSP90AA1TSHRLMNAACHEALDH1A1 | |
| SCHEMBL1818188 | 0.82 | HSP90AA1 (0.74) | HSP90AA1TSHRLMNAACHEALDH1A1 | |
| SCHEMBL8574142 | 0.80 | HSP90AA1 (0.71) | HSP90AA1TSHRLMNAACHEALDH1A1 | |
| SCHEMBL1818189 | 0.80 | HSP90AA1 (0.71) | HSP90AA1TSHRLMNAACHEALDH1A1 | |
| SCHEMBL1145909 | 0.80 | HSP90AA1 (0.71) | HSP90AA1TSHRLMNAACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732534-B2 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION (JP) | 2010-06-08 | — | — | US | claimed |
| US-20080051552-A1 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION | 2008-02-28 | — | — | US | claimed |
| US-20080051519-A1 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION (JP) | 2008-02-28 | — | — | US | claimed |
| US-6989263-B1 | Method for identifying and using compounds that inactivate HIV-1 and other retroviruses by attacking highly conserved zinc fingers in the viral nucleocapsid protein | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2006-01-24 | — | — | US | claimed |
| US-20030198648-A1 | Methods for identifying compounds which inhibit binding of nucleocapsid 7 protein to HIV-1 RNA | ACHILION PHARMACEUTICALS | 2003-10-23 | — | — | US | claimed |
| WO-2003060098-A2 | METHODS FOR IDENTIFYING COMPOUNDS WHICH INHIBIT BINDING OF NUCLEOCAPSID 7 PROTEIN TO HIV-1 RNA | ACHILLION PHARMACEUTICALS, INC. (US) | 2003-07-24 | — | — | WO | claimed |
| EP-0782632-B1 | A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN | US GOV HEALTH & HUMAN SERV (US) | 2003-04-16 | — | — | EP | claimed |
| US-6001555-A | DISSOCIATING A ZINC FINGER BY CONTACTING THE PROTEIN WITH A DISULFIDE, A MALEIMIDE, AN ALPHA-HALOGENATED KETONE, A HYDRAZIDE, A NITRIC OXIDE OR DERIVATIVES, CUPRIC IONS, FERRIC IONS OR THEIR COMPLEXES; SYNERGISTIC EFFECTS WITH VIRICIDES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-12-14 | — | — | US | claimed |
| EP-0782632-A1 | A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the Secretary of the Department of Health and Human Services (US) | 1997-07-09 | — | — | EP | claimed |
| WO-1996009406-A9 | A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN | — | 1996-05-23 | — | — | WO | claimed |
| WO-1996009406-A1 | A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-03-28 | — | — | WO | claimed |
| EP-0693056-A1 | PROCESS FOR THE PREPARATION OF ARYL- AND HETEROARYLSULPHURPENTAFLUORIDES | ZENECA LIMITED (GB) | 1996-01-24 | — | — | EP | claimed |
| WO-1994022817-A1 | PROCESS FOR THE PREPARATION OF ARYL- AND HETEROARYLSULPHURPENTAFLUORIDES | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | claimed |
| CN-116283684-A | Green preparation method of diphenyl sulfide and derivative thereof | 常州大学 | 2023-06-23 | — | — | CN | disclosed |
| WO-2023001999-A1 | C2-THIOETHER TRYPTOPHAN TRIMERS AND TETRAMERS FOR THE TREATMENT OF BETACORONOAVIRUS INFECTIONS | 1. CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2023-01-26 | — | — | WO | disclosed |
| EP-4122917-A1 | C2-THIOETHER TRYPTOPHAN TRIMERS AND TETRAMERS AND USE THEREOF | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2023-01-25 | — | — | EP | disclosed |
| US-4656290-A | Process for preparing thio, dithio or carbonyl compounds | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1987-04-07 | — | — | US | disclosed |
| EP-0150026-A2 | Chemical process | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1985-07-31 | — | — | EP | disclosed |
| US-4286964-A | Polyfunctional epoxides and halohydrins used as bridging groups to bind aromatic amine group-containing alcohols and thiols to hydroxyl bearing substrates | SEED BRIAN S | 1981-09-01 | — | — | US | disclosed |
| EP-0027377-A1 | Derivatives of hydroxyl-bearing substrates, process for their preparation and a method of application | Seed, Brian Sarsfield (US) | 1981-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030198648-A1 | Methods for identifying compounds which inhibit binding of nucleocapsid 7 protein to HIV-1 RNA | MRPS27, SNRPE, NSUN2 | HSP90AA1 2171/4885TSHR 4796/4885LMNA 2733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.