Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31482901 | 0.83 | HSP90AA1 (1.00) | HSP90AA1TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL30468119 | 0.83 | HSP90AA1 (1.00) | HSP90AA1TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL31405188 | 0.83 | HSP90AA1 (0.77) | HSP90AA1TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL288227 | 0.83 | HSP90AA1 (1.00) | HSP90AA1TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL11356136 | 0.83 | HSP90AA1 (0.77) | HSP90AA1TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL20347051 | 0.83 | HSP90AA1 (0.77) | HSP90AA1TSHRLMNAALDH1A1TDP1 | |
| Dinitrophenylene SCHEMBL9683678 | 0.83 | TSHR (0.81) | HSP90AA1TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL1818188 | 0.82 | HSP90AA1 (0.74) | HSP90AA1TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL1818189 | 0.80 | HSP90AA1 (0.71) | HSP90AA1TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL288228 | 0.80 | HSP90AA1 (0.71) | HSP90AA1TSHRLMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821263-A | ANTICARCINOGENIC AGENT; CHARACTERIZED BY C3' NITROGEN BEARING ONE OR TWO SULFUR SUBSTITUENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-13 | — | — | US | disclosed |
| WO-1998008833-A1 | SULFENAMIDE TAXANE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
| EP-0025339-B1 | MICROBICIDAL SULFONES, COMPOSITIONS THEREOF AND METHODS OF PREPARING THEM | UNIROYAL, INC. (US) | 1984-05-30 | — | — | EP | disclosed |
| US-4335142-A | MICROBIOCIDES | UNIROYAL, INC. (US) | 1982-06-15 | — | — | US | disclosed |
| EP-0025339-A1 | Microbicidal sulfones, compositions thereof and methods of preparing them | UNIROYAL, INC. (US) | 1981-03-18 | — | — | EP | disclosed |
| US-4174405-A | MITICIDES | UNIROYAL, INC. (US) | 1979-11-13 | — | — | US | disclosed |
| US-4122089-A | Aminothiofluoran compounds, process for the production thereof, and recording elements containing the same | SANKIO CHEMICAL CO., LTD. (JP) | 1978-10-24 | — | — | US | disclosed |