Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21142414 | 0.79 | GID4 (0.41) | ALDH1A1KDM1ADRD2DRD1DRD4 | |
| SCHEMBL28843549 | 0.79 | CYP1A1 (0.48) | CYP2D6DRD2 | |
| SCHEMBL298038 | 0.77 | DRD2 (0.46) | HTR2CNOTUMALDH1A1KMT2APNMT | |
| SCHEMBL28389193 | 0.72 | ACHE (0.34) | HTR2CTAS1R3TAS1R1TAS1R2ADRA2A | |
| SCHEMBL193434 | 0.72 | HTR2C (0.45) | HTR2CTRPM8NOTUMIDO1KDM1A | |
| SCHEMBL193435 | 0.72 | HTR2C (0.45) | HTR2CTRPM8NOTUMIDO1KDM1A | |
| SCHEMBL31250078 | 0.72 | HTR2C (0.45) | HTR2CTRPM8NOTUMIDO1KDM1A | |
| SCHEMBL11110438 | 0.72 | HTR2C (0.45) | HTR2CTRPM8NOTUMIDO1FFAR1 | |
| SCHEMBL1508419 | 0.72 | HTR2C (0.45) | HTR2CTRPM8NOTUMIDO1FFAR1 | |
| SCHEMBL18204509 | 0.72 | HTR2C (0.45) | HTR2CTRPM8NOTUMIDO1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105358586-A | Cyclopropyl substituted metallocene catalysts | EXXONMOBIL CHEM PATENTS INC | 2016-02-24 | — | — | CN | disclosed |