SCHEMBL28823447

SCHEMBL28823447

C=CCN(C(=O)OC(C)(C)C)c1c(C)ccc2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 4/20 0.37
HPGD P15428 4/20 0.37
ATM Q13315 2/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
MAPT P10636 2/20 0.37
POLB P06746 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
NQO2 P16083 1/20 0.36
NCEH1 Q6PIU2 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GSTO1 P78417 1/20 0.35
CTSS P25774 1/20 0.35
CTSK P43235 1/20 0.35
MCL1 Q07820 1/20 0.35
TSHR P16473 2/20 0.34
NR1D1 P20393 1/20 0.34
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28039129 0.81 NCEH1 (0.43) ALDH1A1KMT2AMEN1MAPTNQO2
SCHEMBL28039122 0.79 NCEH1 (0.41) ALDH1A1KDM4EKMT2ANQO2NCEH1
SCHEMBL28039140 0.79 NCEH1 (0.41) ALDH1A1KDM4EKMT2ANQO2NCEH1
SCHEMBL28823462 0.79 NCEH1 (0.41) ALDH1A1KDM4EKMT2ANQO2NCEH1
SCHEMBL28823481 0.77 L3MBTL1 (0.35) ALDH1A1KDM4EHPGDATMKMT2A
SCHEMBL28038900 0.77 CYP3A4 (0.43) ALDH1A1KMT2AMEN1NPSR1L3MBTL1
SCHEMBL28660212 0.71 KDM4E (0.40) ALDH1A1KDM4EHPGDATMKMT2A
SCHEMBL20297003 0.71 L3MBTL1 (0.35) ALDH1A1KDM4EHPGDATMKMT2A
SCHEMBL28655242 0.71 KDM4E (0.40) ALDH1A1KDM4EHPGDATMKMT2A
SCHEMBL23217979 0.71 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104981249-A Antimicrobial compounds, their synthesis and applications thereof SEC DEP FOR HEALTH 2015-10-14 CN disclosed