Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 13/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 12/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29943765 | 0.81 | ACHE (0.73) | MEN1POLBAPOBEC3AKMT2AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL1071121 | 0.81 | ACHE (0.73) | MEN1POLBAPOBEC3AKMT2AAPOBEC3G | |
| SCHEMBL21381177 | 0.80 | ACHE (0.67) | MEN1POLBAPOBEC3AKMT2AAPOBEC3G | |
| SCHEMBL1127587 | 0.79 | ACHE (0.76) | MEN1POLBAPOBEC3AKMT2AAPOBEC3G | |
| SCHEMBL29729955 | 0.79 | ACHE (0.76) | MEN1POLBAPOBEC3AKMT2AAPOBEC3G | |
| SCHEMBL13996862 | 0.78 | KDM4E (0.59) | MEN1POLBAPOBEC3AKMT2AAPOBEC3G | |
| Bromide SCHEMBL1069897 | 0.78 | ACHE (0.79) | MEN1POLBAPOBEC3AKMT2AAPOBEC3G | |
| SCHEMBL15625753 | 0.77 | BCHE (0.63) | MEN1POLBAPOBEC3AKMT2AAPOBEC3G | |
| SCHEMBL20152086 | 0.76 | ACHE (0.82) | MEN1POLBAPOBEC3AKMT2AAPOBEC3G | |
| Dibromomethane SCHEMBL20836215 | 0.76 | BCHE (0.61) | MEN1POLBAPOBEC3AKMT2AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114958327-A | High-temperature-resistant annular protection corrosion inhibitor and preparation method and application thereof | 中海石油(中国)有限公司湛江分公司 | 2022-08-30 | — | — | CN | disclosed |