Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14875894 | 0.88 | HDAC1 (0.56) | HPGDKDM4EALDH1A1P4HTMAR | |
| SCHEMBL14875819 | 0.87 | ALDH1A1 (0.52) | HPGDKDM4EALDH1A1ARKMT2A | |
| SCHEMBL18135116 | 0.87 | HPGD (0.52) | HPGDKDM4EALDH1A1P4HTMAR | |
| SCHEMBL14876043 | 0.84 | HPGD (0.46) | HPGDKDM4EALDH1A1ARKMT2A | |
| Hydrochloric Acid SCHEMBL14877429 | 0.82 | ANO1 (0.41) | HPGDKDM4EALDH1A1P4HTMKMT2A | |
| SCHEMBL18135095 | 0.82 | HPGD (0.47) | HPGDKDM4EALDH1A1ARKMT2A | |
| SCHEMBL14876084 | 0.79 | KMT2A (0.51) | HPGDKDM4EALDH1A1ARKMT2A | |
| SCHEMBL11479764 | 0.78 | KDM4E (0.51) | HPGDKDM4EALDH1A1ARKMT2A | |
| SCHEMBL17331312 | 0.78 | ALKBH2 (0.55) | ALDH1A1KMT2AMMP2 | |
| Hydrochloric Acid SCHEMBL14876520 | 0.78 | KMT2A (0.50) | HPGDKDM4EALDH1A1KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958475-B | Heteroaryl hydroxamic acid derivatives and their use in the treatment, alleviation or prevention of viral diseases | F. HOFFMANN-LA ROCHE AG (CH) | 2015-11-25 | — | — | CN | disclosed |