Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.47 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29817656 | 1.00 | RORC (0.57) | RORCTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL29817735 | 0.85 | RORC (0.57) | RORCTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL28157214 | 0.85 | RORC (0.57) | RORCTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL28823959 | 0.80 | RORC (0.63) | RORCTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL28843210 | 0.79 | ALDH1A1 (0.65) | RORCTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL29935433 | 0.79 | ALDH1A1 (0.65) | RORCTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL29817839 | 0.79 | RORC (0.62) | RORCTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL28156624 | 0.79 | RORC (0.62) | RORCTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL29817649 | 0.79 | TSHR (0.57) | RORCTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL28157206 | 0.79 | TSHR (0.57) | RORCTSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114790169-A | Tetrahydroquinoline related bicyclic compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2022-07-26 | — | — | CN | disclosed |