Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824000 | 0.88 | LMNA (0.45) | SCN9AALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL28824024 | 0.85 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2POLBHPGDKDM4E | |
| SCHEMBL28824098 | 0.84 | BCAT2 (0.45) | SCN9AALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL8156087 | 0.80 | TP53 (0.58) | ALDH1A1SMN1; SMN2HPGDKDM4EHSD17B10 | |
| SCHEMBL28824074 | 0.79 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2POLBHPGDKDM4E | |
| SCHEMBL6765042 | 0.77 | KDM4E (0.54) | ALDH1A1SMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL28824021 | 0.77 | LMNA (0.44) | ALDH1A1SMN1; SMN2POLBHPGDKDM4E | |
| SCHEMBL28823986 | 0.75 | FOLH1 (0.44) | SMN1; SMN2KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL28824025 | 0.75 | NPC1 (0.39) | ALDH1A1SMN1; SMN2POLBHPGDNPC1 | |
| SCHEMBL8156170 | 0.74 | IDO1 (0.46) | ALDH1A1SMN1; SMN2POLBHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |