SCHEMBL10709571

SCHEMBL10709571

CCOP(c1ccc(C)cc1)c1ccc(C)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.38
TDP1 Q9NUW8 1/20 0.38
AGXT P21549 2/20 0.33
ALDH1A1 P00352 3/20 0.32
LMNA P02545 1/20 0.32
IDO1 P14902 1/20 0.32
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
MAPT P10636 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
DHODH Q02127 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30437039 0.82 ACHE (0.35) ACHETDP1AGXTALDH1A1LMNA
SCHEMBL6867317 0.81 ACHE (0.38) ACHETDP1AGXTALDH1A1IDO1
SCHEMBL7778608 0.79 TDP1 (0.36) ACHETDP1AGXTLMNAIDO1
SCHEMBL30356616 0.79 TP53 (0.39) TDP1ALDH1A1LMNAIDO1SMN1; SMN2
SCHEMBL11277499 0.79 LMNA (0.36) TDP1AGXTALDH1A1LMNAIDO1
SCHEMBL25214920 0.79 LMNA (0.40) ACHEALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL196443 0.78 CYP3A4 (0.39) TDP1ALDH1A1CYP3A4
SCHEMBL25199142 0.78 ALDH1A1 (0.33) TDP1ALDH1A1CYP3A4
SCHEMBL28449185 0.77 CA1 (0.48) ACHETDP1AGXTALDH1A1IDO1
SCHEMBL10439916 0.77 ACHE (0.35) ACHETDP1AGXTIDO1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362338-A Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound 湖南理工学院 2024-01-09 CN claimed
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US claimed
CN-117362338-A Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound 湖南理工学院 2024-01-09 CN disclosed
CN-111518145-B Cyano-bridged metal organic compound with intramolecular magnetic transformation and preparation method and application thereof 荆楚理工学院 2023-06-20 CN disclosed
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US disclosed
CN-115925743-A Method for preparing (2-oxo-2-aryl ethyl) diaryl phosphine oxide compound 湖南理工学院 2023-04-07 CN disclosed
EP-0110089-B1 POLYMER-BOUND ALKYL DIARYLPHOSPHINITE CATALYST COMPOSITIONS AND PROCESSES FOR MAKING SAME AND USING SAME FOR SELECTIVE CONVERSION OF ACRYLONITRILE INTO 1,4-DICYANO-1-BUTENE ALLIED CORPORATION (US) 1988-01-07 EP disclosed
US-4710545-A REACTING CROSSLINKED DIVINYLBENZENE-STYRENE COPOLYMER WITH A PHOSPHORUS HALIDE, AROMATIC COMPOUND, WATER AND AN ALCOHOL ALLIED CORPORATION (US) 1987-12-01 US disclosed
US-4661615-A DIMERIZATION ALLIED CORPORATION (US) 1987-04-28 US disclosed
US-4581415-A DIMERIZATION OF ACRYLONITRILE; CATALYST SELECTIVITY; DURABILITY ALLIED CORPORATION (US) 1986-04-08 US disclosed
US-4574060-A Selective conversion of acrylonitrile into 1,4-dicyano-1-butene catalyzed by polymer-bound alkyl diarylphosphinites ALLIED CORPORATION (US) 1986-03-04 US disclosed
EP-0110089-A2 Polymer-bound alkyl diarylphosphinite catalyst compositions and processes for making same and using same for selective conversion of acrylonitrile into 1,4-dicyano-1-butene ALLIED CORPORATION (US) 1984-06-13 EP disclosed
US-4257973-A USING ORGANOPHOSPHORUS-PALLADIUM HALIDE COORDINATION CATALYST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-03-24 US disclosed