Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.58 |
| ▸ | LAP3 | P28838 | 3/20 | 0.55 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.51 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.51 |
| ▸ | GRN | P28799 | 1/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15302480 | 1.00 | ALDH1A1 (0.72) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL13838843 | 1.00 | ALDH1A1 (0.72) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL28214706 | 0.86 | ALDH1A1 (0.88) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL13785341 | 0.86 | ALDH1A1 (0.72) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| Acetylleucine SCHEMBL282371 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL22355918 | 0.84 | FOLH1 (0.52) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL27847904 | 0.84 | FOLH1 (0.76) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| Levacetylleucine SCHEMBL9438432 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| Levacetylleucine SCHEMBL714003 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| Levacetylleucine SCHEMBL282372 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MEN1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110652595-B | Poly leucine-poly aspartic acid segmented copolymer stereo composite drug-loaded micelle and preparation method thereof | 南通大学附属医院 | 2022-11-29 | — | — | CN | claimed |
| CN-114805496-B | Group of non-ribosomal polypeptide (NRPs) compounds, preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-06-21 | — | — | CN | disclosed |
| CN-110652595-B | Poly leucine-poly aspartic acid segmented copolymer stereo composite drug-loaded micelle and preparation method thereof | 南通大学附属医院 | 2022-11-29 | — | — | CN | disclosed |
| CN-114805496-A | Non-ribosomal polypeptide (NRPs) compounds, preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2022-07-29 | — | — | CN | disclosed |