Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1557265 | 0.85 | LTA4H (0.45) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7453614 | 0.84 | POLB (0.41) | POLB | |
| SCHEMBL2955083 | 0.81 | XDH (0.46) | XDHMEN1KMT2AKCNH2SCN5A | |
| SCHEMBL28824294 | 0.81 | KCNH2 (0.46) | XDHKCNH2SCN5ASCN9A | |
| SCHEMBL29707595 | 0.81 | KCNH2 (0.46) | XDHKCNH2SCN5ASCN9A | |
| SCHEMBL1555903 | 0.81 | LTA4H (0.48) | HTTRAB9AXDHTDP1 | |
| SCHEMBL23576461 | 0.81 | TGFBR1 (0.39) | TDP1KMT2A | |
| SCHEMBL29972518 | 0.81 | TGFBR1 (0.39) | TDP1KMT2A | |
| SCHEMBL23087952 | 0.81 | XDH (0.49) | HTTXDHALDH1A1MAPTTDP1 | |
| SCHEMBL23087206 | 0.80 | SMN1; SMN2 (0.46) | HTTRAB9ASMN1; SMN2PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805192-A | Tricyclic XOR/URAT1 dual inhibitor containing 2-hydroxybenzoic acid and preparation method and application thereof | 华南理工大学 | 2022-07-29 | — | — | CN | disclosed |