Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4938372 | 0.83 | LMNA (0.68) | LMNATDP1TRPV6CYP19A1ALDH1A1 | |
| Pyridine SCHEMBL11782749 | 0.83 | TRPV6 (0.52) | LMNATDP1TRPV6ALDH1A1SMN1; SMN2 | |
| SCHEMBL16301357 | 0.83 | LMNA (0.68) | LMNATDP1TRPV6CYP19A1ALDH1A1 | |
| SCHEMBL103152 | 0.83 | LMNA (0.68) | LMNATDP1TRPV6CYP19A1ALDH1A1 | |
| SCHEMBL6201445 | 0.81 | LMNA (0.64) | LMNATDP1TRPV6CYP19A1ALDH1A1 | |
| SCHEMBL10544332 | 0.80 | LMNA (0.62) | LMNATDP1TRPV6CYP19A1ALDH1A1 | |
| SCHEMBL10549969 | 0.80 | LMNA (0.62) | LMNATDP1TRPV6CYP19A1ALDH1A1 | |
| SCHEMBL22910536 | 0.80 | LMNA (0.62) | LMNATDP1TRPV6CYP19A1ALDH1A1 | |
| SCHEMBL10223959 | 0.80 | LMNA (0.62) | LMNATDP1TRPV6CYP19A1ALDH1A1 | |
| SCHEMBL202774 | 0.78 | ALDH1A1 (0.54) | TDP1TRPV6ALDH1A1SMN1; SMN2CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805192-A | Tricyclic XOR/URAT1 dual inhibitor containing 2-hydroxybenzoic acid and preparation method and application thereof | 华南理工大学 | 2022-07-29 | — | — | CN | disclosed |