Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28159338 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL28043035 | 0.76 | PIK3CA (0.33) | — | |
| SCHEMBL16398389 | 0.69 | HTR2A (0.34) | — | |
| SCHEMBL16398164 | 0.66 | FFAR1 (0.34) | — | |
| SCHEMBL16398055 | 0.65 | IDH1 (0.42) | — | |
| SCHEMBL3934799 | 0.64 | BACE1 (0.38) | — | |
| SCHEMBL16398534 | 0.63 | NUDT1 (0.42) | — | |
| SCHEMBL16397929 | 0.61 | MALT1 (0.37) | — | |
| SCHEMBL16397831 | 0.61 | TACR1 (0.36) | — | |
| SCHEMBL4716506 | 0.61 | HRH4 (0.38) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263923-A | Pyrimidine compounds and their use as gamma secretase modulators | Acturum Life Science AB | 2016-01-20 | — | — | CN | disclosed |