Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | DDO | Q99489 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 3/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1866724 | 0.85 | TTR (0.44) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2226759 | 0.85 | TTR (0.44) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1683777 | 0.83 | ALDH1A1 (0.45) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL31454166 | 0.83 | ALDH1A1 (0.45) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7770944 | 0.82 | KDM4E (0.44) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7589533 | 0.82 | TPMT (0.46) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL32679274 | 0.80 | ALDH1A1 (0.50) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2725031 | 0.80 | ALDH1A1 (0.50) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10605792 | 0.80 | LMNA (0.42) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7596506 | 0.80 | TPMT (0.45) | KDM4EMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102432-A | Substituted benzene compounds | EPIZYME INC | 2015-11-25 | — | — | CN | disclosed |