Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | DDO | Q99489 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 3/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518116 | 0.87 | LOXL2 (0.44) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL934326 | 0.87 | LOXL2 (0.44) | KDM4EALDH1A1LMNATPMTLOXL2 | |
| SCHEMBL28177112 | 0.86 | LNPEP (0.44) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL31454166 | 0.85 | ALDH1A1 (0.45) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1683777 | 0.85 | ALDH1A1 (0.45) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9139047 | 0.85 | LOXL2 (0.43) | KDM4EALDH1A1LMNATPMTLOXL2 | |
| Hydrochloric Acid SCHEMBL22400384 | 0.85 | LOXL2 (0.43) | KDM4EALDH1A1LMNATPMTLOXL2 | |
| SCHEMBL7589533 | 0.83 | TPMT (0.46) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL3503704 | 0.83 | TSHR (0.39) | LMNALOXL2PLAUSMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL7596506 | 0.82 | TPMT (0.45) | KDM4EALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121378-A1 | A PROCESS FOR THE PREPARATION OF A THROMBUS IMAGING AGENT | Du Pont Pharmaceuticals Company (US) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000021982-A1 | A PROCESS FOR THE PREPARATION OF A THROMBUS IMAGING AGENT | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-04-20 | — | — | WO | disclosed |
| US-6022523-A | NOVEL CYCLIC COMPOUNDS CONTAINING CARBOCYCLIC AND HETEROCYCLIC RING SYSTEMS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-02-08 | — | — | US | disclosed |