Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825902 | 0.86 | LDHA (0.40) | ALDH1A1 | |
| SCHEMBL28045730 | 0.86 | CTSK (0.37) | ALDH1A1LMNANPSR1 | |
| SCHEMBL28027057 | 0.76 | CYP19A1 (0.30) | — | |
| SCHEMBL27729633 | 0.76 | — | — | |
| SCHEMBL28000370 | 0.76 | CTSK (0.36) | — | |
| SCHEMBL28268882 | 0.75 | — | — | |
| SCHEMBL28262437 | 0.73 | CYP19A1 (0.44) | ALDH1A1LMNA | |
| SCHEMBL27977725 | 0.73 | AKR1B1 (0.33) | ALDH1A1 | |
| SCHEMBL28829366 | 0.72 | — | — | |
| SCHEMBL28265331 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105121432-A | Heterocyclic amides as kinase inhibitors | GLAXOSMITHKLINE IP DEV LTD | 2015-12-02 | — | — | CN | disclosed |