Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.37 |
| ▸ | CTSL | P07711 | 4/20 | 0.36 |
| ▸ | CTSB | P07858 | 4/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CTSH | P09668 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.31 |
| ▸ | ACP3 | P15309 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALPI | P09923 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824696 | 0.86 | ALDH1A1 (0.32) | ALDH1A1LMNANPSR1 | |
| SCHEMBL28825902 | 0.83 | LDHA (0.40) | CYP1A2ALDH1A1 | |
| SCHEMBL18085416 | 0.82 | EPHX1 (0.48) | CTSKCTSLCTSBEPHX1MEN1 | |
| SCHEMBL27977725 | 0.81 | AKR1B1 (0.33) | MEN1KMT2AALDH1A1 | |
| SCHEMBL28061404 | 0.78 | EPHX1 (0.35) | CTSKCTSLCTSBEPHX1MEN1 | |
| SCHEMBL28113598 | 0.78 | CTSK (0.34) | CTSKCTSLCTSBEPHX1MEN1 | |
| SCHEMBL28268882 | 0.78 | — | — | |
| SCHEMBL28827075 | 0.78 | GLS (0.32) | — | |
| SCHEMBL28074772 | 0.77 | CTSK (0.36) | CTSKCTSLCTSBEPHX1MEN1 | |
| SCHEMBL28113592 | 0.75 | TSHR (0.42) | CTSKEPHX1MEN1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105121432-A | Heterocyclic amides as kinase inhibitors | GLAXOSMITHKLINE IP DEV LTD | 2015-12-02 | — | — | CN | disclosed |