Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29808658 | 1.00 | TRPM8 (0.40) | TRPM8SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL23295658 | 1.00 | TRPM8 (0.40) | TRPM8SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL30674901 | 1.00 | TRPM8 (0.40) | TRPM8SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL10124296 | 1.00 | TRPM8 (0.40) | TRPM8SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL31068984 | 0.85 | TRPM8 (0.40) | TRPM8SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL2627815 | 0.85 | TRPM8 (0.40) | TRPM8SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL26271641 | 0.79 | TRPM8 (0.37) | TRPM8SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL27140480 | 0.79 | TRPM8 (0.37) | TRPM8SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL23006312 | 0.79 | TRPM8 (0.37) | TRPM8SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL29857523 | 0.77 | NOS3 (0.45) | SMN1; SMN2KDM4EHSP90AA1HTTPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114934083-A | Preparation method of high-purity (S) -1- (pyridine-2-yl) ethanol derivative | 重庆张邦医药科技有限责任公司 | 2022-08-23 | — | — | CN | disclosed |