Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.37 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 3/20 | 0.35 |
| ▸ | F3 | P13726 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12802010 | 0.83 | LIPG (0.48) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL12802299 | 0.81 | LIPG (0.52) | THRATHRBLIPGALOX5PTGS2 | |
| Hydrochloric Acid SCHEMBL2898929 | 0.78 | LIPG (0.53) | THRATHRBLIPGALOX5PTGS2 | |
| Hydrochloric Acid SCHEMBL11542002 | 0.78 | LIPG (0.53) | THRATHRBLIPGALOX5PTGS2 | |
| Hydrochloric Acid SCHEMBL28853938 | 0.78 | LIPG (0.53) | THRATHRBLIPGALOX5PTGS2 | |
| Hydrochloric Acid SCHEMBL5072856 | 0.78 | LIPG (0.53) | THRATHRBLIPGALOX5PTGS2 | |
| Hydrochloric Acid SCHEMBL28880990 | 0.78 | LIPG (0.53) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL12802233 | 0.77 | CYP3A4 (0.42) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL21055952 | 0.77 | LIPG (0.43) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL2904403 | 0.76 | LIPG (0.55) | THRATHRBLIPGALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105339440-A | Inks | FUJIFILM IMAGING COLORANTS INC | 2016-02-17 | — | — | CN | disclosed |
| CN-105339444-A | Printing method | FUJIFILM IMAGING COLORANTS INC | 2016-02-17 | — | — | CN | disclosed |