Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047721 | 1.00 | LMNA (0.40) | LMNAHTR1AADRA2ACYP2D6ADRA2C | |
| SCHEMBL28047791 | 1.00 | LMNA (0.40) | LMNAHTR1AADRA2ACYP2D6ADRA2C | |
| SCHEMBL28825360 | 0.83 | TP53 (0.47) | LMNAPKMPDE4D | |
| SCHEMBL28047700 | 0.83 | TP53 (0.47) | LMNAPKMPDE4D | |
| SCHEMBL28047713 | 0.83 | TP53 (0.47) | LMNAPKMPDE4D | |
| SCHEMBL28047701 | 0.74 | CYP3A4 (0.61) | CYP2D6 | |
| SCHEMBL28047859 | 0.74 | FFAR1 (0.41) | — | |
| SCHEMBL10887701 | 0.72 | ALDH1A1 (0.45) | LMNAADRA2CPKM | |
| SCHEMBL28047757 | 0.72 | ALDH1A1 (0.45) | LMNAADRA2CPKM | |
| SCHEMBL7198348 | 0.70 | CYP3A4 (0.46) | LMNAHTR1AADRA2ACYP2D6ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | disclosed |