Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825360 | 1.00 | TP53 (0.47) | TP53PKMPTPN1SMN1; SMN2LMNA | |
| SCHEMBL28047713 | 1.00 | TP53 (0.47) | TP53PKMPTPN1SMN1; SMN2LMNA | |
| SCHEMBL28047721 | 0.83 | LMNA (0.40) | PKMLMNAPDE4D | |
| SCHEMBL28047791 | 0.83 | LMNA (0.40) | PKMLMNAPDE4D | |
| SCHEMBL28825355 | 0.83 | LMNA (0.40) | PKMLMNAPDE4D | |
| SCHEMBL27982705 | 0.81 | TP53 (0.62) | TP53PKMSMN1; SMN2LMNAHTT | |
| Hydrochloric Acid SCHEMBL28047706 | 0.80 | TP53 (0.61) | TP53PKMSMN1; SMN2LMNAHTT | |
| SCHEMBL11592980 | 0.79 | ALDH1A1 (0.47) | TP53PKMPTPN1LMNAHTT | |
| SCHEMBL4211850 | 0.78 | KDM4E (0.53) | PKMLMNARAB9AALDH1A1 | |
| SCHEMBL1043148 | 0.77 | PKM (0.49) | TP53PKMPTPN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | disclosed |