Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 17/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 16/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 8/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825467 | 0.82 | GRIN1 (0.42) | GRIN2BGRIN1RAB9AKMT2ARXRA | |
| SCHEMBL28825490 | 0.81 | GRIN2B (0.41) | GRIN2BGRIN1RXRAKCNH2 | |
| SCHEMBL28825500 | 0.80 | RAB9A (0.40) | GRIN2BGRIN1RAB9AKMT2A | |
| SCHEMBL28825512 | 0.80 | GRIN1 (0.42) | GRIN2BGRIN1RAB9AKMT2AGAA | |
| SCHEMBL28825529 | 0.77 | GRIN2B (0.41) | GRIN2BGRIN1RXRAKCNH2 | |
| SCHEMBL28825533 | 0.76 | GRIN2B (0.41) | GRIN2BGRIN1RXRAKCNH2 | |
| SCHEMBL28825646 | 0.75 | GRIN2B (0.41) | GRIN2BGRIN1RXRAKCNH2 | |
| SCHEMBL28825610 | 0.74 | GRIN1 (0.45) | GRIN2BGRIN1RXRA | |
| SCHEMBL30112658 | 0.73 | GRIN2B (0.52) | GRIN2BGRIN1KCNH2 | |
| SCHEMBL28825619 | 0.72 | GRIN2B (0.37) | GRIN2BGRIN1RXRAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | disclosed |