Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 7/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28949587 | 0.83 | GRIN2B (0.40) | GRIN2BGRIN1PDE4BKLKB1GAA | |
| SCHEMBL28825565 | 0.80 | GRIN2B (0.43) | GRIN2BGRIN1KLKB1KLK7GAA | |
| SCHEMBL28825448 | 0.78 | GAA (0.47) | GRIN2BGRIN1PDE4BKLKB1KLK7 | |
| SCHEMBL28825653 | 0.78 | GAA (0.44) | GRIN2BGRIN1PDE4BKLKB1GAA | |
| SCHEMBL28825549 | 0.76 | GRIN2B (0.40) | GRIN2BGRIN1PDE4BKLKB1KLK7 | |
| SCHEMBL28949563 | 0.75 | PDE4B (0.46) | GRIN2BGRIN1PDE4BGAAMAPT | |
| SCHEMBL28825445 | 0.73 | GRIN2B (0.51) | GRIN2BGRIN1KLKB1CYP1A2CYP2C9 | |
| SCHEMBL28825510 | 0.71 | GRIN2B (0.52) | GRIN2BGRIN1KLKB1GAAMAPT | |
| SCHEMBL28825487 | 0.71 | GRIN2B (0.51) | GRIN2BGRIN1KLKB1GAAMAPT | |
| SCHEMBL1457252 | 0.68 | GAA (0.51) | KLKB1GAAMAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | disclosed |