Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 14/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825565 | 0.93 | GRIN2B (0.43) | GRIN2BGRIN1KLKB1 | |
| SCHEMBL28949569 | 0.84 | GRIN2B (0.38) | GRIN2BGRIN1KCNH2KLKB1 | |
| SCHEMBL28825483 | 0.81 | GRIN2B (0.44) | GRIN2BGRIN1 | |
| SCHEMBL28825615 | 0.81 | GRIN2B (0.46) | GRIN2BGRIN1KCNH2CYP1A2CYP2C9 | |
| SCHEMBL28825510 | 0.77 | GRIN2B (0.52) | GRIN2BGRIN1KCNH2CYP1A2CYP2C9 | |
| SCHEMBL28825487 | 0.76 | GRIN2B (0.51) | GRIN2BGRIN1KCNH2CYP1A2CYP2C9 | |
| SCHEMBL28825573 | 0.73 | GRIN2B (0.41) | GRIN2BGRIN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28825549 | 0.72 | GRIN2B (0.40) | GRIN2BGRIN1KLKB1 | |
| SCHEMBL28028438 | 0.68 | MAPT (0.35) | GRIN2BGRIN1CYP1A2KLKB1 | |
| SCHEMBL14822759 | 0.68 | RIPK1 (0.44) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | disclosed |