Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 19/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 16/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | RXRA | P19793 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28949605 | 0.88 | GRIN2B (0.42) | GRIN2BGRIN1KCNH2RXRA | |
| SCHEMBL28825646 | 0.86 | GRIN2B (0.41) | GRIN2BGRIN1KCNH2RXRA | |
| SCHEMBL28825583 | 0.85 | GRIN2B (0.44) | GRIN2BGRIN1KCNH2RXRA | |
| SCHEMBL28825527 | 0.85 | GRIN2B (0.44) | GRIN2BGRIN1KCNH2RXRA | |
| SCHEMBL28825617 | 0.83 | GRIN2B (0.46) | GRIN2BGRIN1KCNH2RXRA | |
| SCHEMBL28825534 | 0.81 | GRIN2B (0.44) | GRIN2BGRIN1KCNH2RXRA | |
| SCHEMBL28825640 | 0.77 | GRIN2B (0.47) | GRIN2BGRIN1KCNH2RXRA | |
| SCHEMBL28825661 | 0.75 | GRIN1 (0.41) | GRIN2BGRIN1RXRA | |
| SCHEMBL28825631 | 0.73 | ALDH1A1 (0.39) | GRIN2BGRIN1 | |
| SCHEMBL10914962 | 0.71 | ALDH1A1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | disclosed |