Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CDK4 | P11802 | 3/20 | 0.46 |
| ▸ | CCND1 | P24385 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26768225 | 0.78 | KDM4E (0.60) | PARP15PARP14PARP10TNKS2PARP2 | |
| SCHEMBL29853502 | 0.78 | KDM4E (0.60) | PARP15PARP14PARP10TNKS2PARP2 | |
| SCHEMBL3501509 | 0.74 | GRIN2D (0.53) | PARP15PARP14PARP10TNKS2PARP2 | |
| SCHEMBL28311148 | 0.74 | ALDH1A1 (0.42) | PARP15PARP14PARP10TNKS2PARP2 | |
| SCHEMBL1470937 | 0.74 | PARP15 (0.52) | PARP15PARP14PARP10TNKS2PARP2 | |
| SCHEMBL28588654 | 0.74 | ALDH1A1 (0.68) | PARP15PARP14PARP10TNKS2PARP2 | |
| SCHEMBL29853659 | 0.73 | PARP15 (0.58) | PARP15PARP14PARP10TNKS2PARP2 | |
| SCHEMBL26785799 | 0.73 | PARP15 (0.58) | PARP15PARP14PARP10TNKS2PARP2 | |
| SCHEMBL13728289 | 0.72 | PARP15 (0.47) | PARP15PARP14PARP10TNKS2PARP2 | |
| SCHEMBL1072455 | 0.72 | CA2 (0.56) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101754974-B | As the macrocylc compound of antiviral agent | MSD ITALIA S.R.L. (IT) | 2016-02-03 | — | — | CN | disclosed |