Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | F12 | P00748 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27970673 | 0.96 | KMT2A (0.33) | SNCAMEN1KMT2AF2LMNA | |
| SCHEMBL28061261 | 0.96 | KMT2A (0.33) | SNCAMEN1KMT2AF2LMNA | |
| SCHEMBL28016232 | 0.94 | MEN1 (0.32) | SNCAMEN1KMT2AF2LMNA | |
| SCHEMBL28069546 | 0.89 | — | — | |
| Zinc Ion SCHEMBL28819502 | 0.88 | CES2 (0.34) | MEN1KMT2AF2LMNAESR2 | |
| SCHEMBL28295478 | 0.87 | — | — | |
| Terephthalic Acid SCHEMBL28007787 | 0.85 | CA2 (0.47) | MEN1KMT2A | |
| Terephthalic Acid SCHEMBL28067237 | 0.84 | TSHR (0.45) | PKM | |
| Acetic Acid SCHEMBL28062766 | 0.83 | CA2 (0.36) | MEN1KMT2AF2LMNAESR1 | |
| SCHEMBL27916776 | 0.81 | MEN1 (0.40) | MEN1KMT2AF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418650-A | Potential fluorescent material tetraphenyl ethylene tetratriazole zinc bromide complex and preparing method thereof | UNIV TIANJIN | 2016-03-23 | — | — | CN | disclosed |
| CN-105418650-A | Potential fluorescent material tetraphenyl ethylene tetratriazole zinc bromide complex and preparing method thereof | UNIV TIANJIN | 2016-03-23 | — | — | CN | disclosed |