Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344491 | 0.84 | POLB (0.47) | POLBTXNRD1ALDH1A1LMNATDP1 | |
| SCHEMBL10911117 | 0.81 | TXNRD1 (0.48) | POLBTXNRD1ALDH1A1LMNATDP1 | |
| SCHEMBL29812082 | 0.81 | TXNRD1 (0.48) | POLBTXNRD1ALDH1A1LMNATDP1 | |
| SCHEMBL23144440 | 0.80 | ALDH1A1 (0.43) | TXNRD1ALDH1A1LMNATDP1SIRT6 | |
| SCHEMBL29812224 | 0.80 | ALDH1A1 (0.43) | TXNRD1ALDH1A1LMNATDP1SIRT6 | |
| SCHEMBL28826094 | 0.79 | MAPT (0.49) | POLBALDH1A1TDP1GAAKMT2A | |
| SCHEMBL30612682 | 0.78 | ALDH1A1 (0.54) | POLBALDH1A1LMNATDP1CHEK1 | |
| SCHEMBL15823469 | 0.78 | ALDH1A1 (0.54) | POLBALDH1A1LMNATDP1CHEK1 | |
| SCHEMBL28217544 | 0.78 | ALDH1A1 (0.45) | POLBTXNRD1ALDH1A1LMNATDP1 | |
| SCHEMBL17550644 | 0.77 | POLB (0.60) | POLBALDH1A1TDP1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115003299-A | Methods and compounds for restoring function of mutant p53 | 皮姆维制药公司 | 2022-09-02 | — | — | CN | disclosed |