Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.56 |
| ▸ | TXNRD3 | Q86VQ6 | 3/20 | 0.56 |
| ▸ | TXNRD2 | Q9NNW7 | 3/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TFEB | P19484 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053798 | 0.86 | NFE2L2 (0.57) | TXNRD1TXNRD3TXNRD2NFE2L2CYP1A1 | |
| SCHEMBL28151166 | 0.86 | NFE2L2 (0.57) | TXNRD1TXNRD3TXNRD2NFE2L2CYP1A1 | |
| SCHEMBL9665310 | 0.84 | NFE2L2 (0.63) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9000303 | 0.84 | NFE2L2 (0.63) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL4019329 | 0.80 | NFE2L2 (0.79) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL1603719 | 0.80 | NFE2L2 (0.79) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7915752 | 0.80 | NFE2L2 (0.79) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL22721963 | 0.76 | CHAT (0.45) | TXNRD1TXNRD3TXNRD2NFE2L2CYP1A1 | |
| SCHEMBL22721962 | 0.76 | CHAT (0.45) | TXNRD1TXNRD3TXNRD2NFE2L2CYP1A1 | |
| SCHEMBL28053936 | 0.75 | PTGS1 (0.50) | PTGS1PTGS2TP53KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103864768-B | Ligustrazine stilbenoids derivatives and preparation method thereof and application | GUANGXI NORMAL UNIVERSITY (CN) | 2016-04-06 | — | — | CN | disclosed |