Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.57 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.55 |
| ▸ | TXNRD3 | Q86VQ6 | 2/20 | 0.55 |
| ▸ | TXNRD2 | Q9NNW7 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28151166 | 1.00 | NFE2L2 (0.57) | NFE2L2TXNRD1TXNRD3TXNRD2HSD17B10 | |
| SCHEMBL28826352 | 0.86 | TXNRD1 (0.56) | NFE2L2TXNRD1TXNRD3TXNRD2KDM4E | |
| SCHEMBL118591 | 0.82 | NFE2L2 (0.79) | NFE2L2HSD17B10KDM4EMAPTCYP1A1 | |
| SCHEMBL615385 | 0.77 | NFE2L2 (0.77) | NFE2L2HSD17B10KDM4EMAPTCYP1A1 | |
| SCHEMBL4713133 | 0.76 | NPC1 (0.64) | NFE2L2HSD17B10KDM4EMAPTCYP1A1 | |
| SCHEMBL4713137 | 0.76 | NPC1 (0.64) | NFE2L2HSD17B10KDM4EMAPTCYP1A1 | |
| SCHEMBL5182341 | 0.75 | NFE2L2 (0.69) | NFE2L2HSD17B10KDM4EMAPTCYP1A1 | |
| SCHEMBL21798669 | 0.73 | NFE2L2 (0.66) | NFE2L2HSD17B10KDM4EMAPTCYP1A1 | |
| SCHEMBL14518616 | 0.73 | NFE2L2 (0.66) | NFE2L2HSD17B10KDM4EMAPTCYP1A1 | |
| SCHEMBL7870072 | 0.73 | NFE2L2 (0.66) | NFE2L2HSD17B10KDM4EMAPTCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106902118-A | A kind of new application of ligustrazine stilbenoids derivatives | 天津中医药大学 | 2017-06-30 | — | — | CN | disclosed |
| CN-103864768-B | Ligustrazine stilbenoids derivatives and preparation method thereof and application | GUANGXI NORMAL UNIVERSITY (CN) | 2016-04-06 | — | — | CN | disclosed |