Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.63 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | TFEB | P19484 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | LYN | P07948 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000303 | 1.00 | NFE2L2 (0.63) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL1603719 | 0.87 | NFE2L2 (0.79) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7915752 | 0.87 | NFE2L2 (0.79) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL4019329 | 0.87 | NFE2L2 (0.79) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL28826352 | 0.84 | TXNRD1 (0.56) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9168170 | 0.79 | NFE2L2 (0.88) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9168164 | 0.79 | NFE2L2 (0.88) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL713258 | 0.78 | NFE2L2 (1.00) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL713256 | 0.78 | NFE2L2 (1.00) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL19076184 | 0.77 | NFE2L2 (0.59) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516409-A2 | Tetravinylpyrazine compound, method for preparing same and electroluminescent element and non-linear optical material using same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-12-02 | — | — | EP | disclosed |