Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29082679 | 0.82 | NPC1 (0.50) | NR1H4NPC1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL27851482 | 0.82 | MAPT (0.48) | NPC1SMN1; SMN2KDM4ERAB9ATDP1 | |
| SCHEMBL27868449 | 0.82 | ALDH1A1 (0.53) | NPC1SMN1; SMN2KDM4ERAB9ANPSR1 | |
| SCHEMBL27851505 | 0.80 | MAPT (0.45) | NR1H4NPC1SMN1; SMN2RAB9APOLB | |
| SCHEMBL29082692 | 0.76 | NOTUM (0.46) | SUCNR1QPCTNPC1SMN1; SMN2KDM4E | |
| SCHEMBL6605688 | 0.75 | NR1H4 (0.52) | SUCNR1NR1H4QPCTNPC1SMN1; SMN2 | |
| SCHEMBL5901252 | 0.74 | ALDH1A1 (0.62) | SUCNR1NR1H4QPCTNPC1SMN1; SMN2 | |
| SCHEMBL21590146 | 0.74 | NPC1 (0.51) | SUCNR1NR1H4QPCTNPC1SMN1; SMN2 | |
| SCHEMBL3825450 | 0.74 | NOTUM (0.62) | SUCNR1NR1H4QPCTNPC1SMN1; SMN2 | |
| SCHEMBL13899158 | 0.74 | NOTUM (0.62) | SUCNR1NR1H4QPCTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103209979-B | therapeutic agent 976 | ASTRAZENECA AB (SE) | 2016-02-10 | — | — | CN | disclosed |