Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421353 | 0.83 | PPARG (0.43) | PDE4APDE4BPDE4CPDE4DAGTR1 | |
| SCHEMBL245599 | 0.77 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DAGTR1 | |
| SCHEMBL7422046 | 0.77 | AGTR1 (0.41) | PDE4APDE4BPDE4CPDE4DAGTR1 | |
| SCHEMBL245600 | 0.75 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DAGTR1 | |
| SCHEMBL7423441 | 0.67 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DAGTR1 | |
| SCHEMBL7423304 | 0.65 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DAGTR1 | |
| SCHEMBL244242 | 0.65 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DAGTR1 | |
| SCHEMBL27780658 | 0.65 | KCNH2 (0.40) | — | |
| SCHEMBL9845720 | 0.65 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL28451245 | 0.64 | PIK3CD (0.50) | PDE4APDE4BPDE4CPDE4DTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102861019-B | The medicine for the treatment of or prevention neuropathic pain | NOVARTIS AG (CH) | 2016-05-25 | — | — | CN | disclosed |
| CN-102885818-B | The method for the treatment of or prophylaxis inflammatory pain | NOVARTIS AG (CH) | 2016-05-04 | — | — | CN | disclosed |