Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | CASR | P41180 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21028899 | 0.78 | PIK3CD (0.60) | PIK3CDLMNAMAPTMEN1CYP1A2 | |
| SCHEMBL16597165 | 0.78 | PIK3CD (0.79) | PIK3CDLMNAMAPTPDE4DHPGD | |
| SCHEMBL11923470 | 0.78 | PIK3CD (0.50) | PIK3CDCASRELANELMNAHSD17B10 | |
| SCHEMBL16597161 | 0.77 | ALDH1A1 (0.48) | PIK3CDCASRELANELMNAMAPT | |
| SCHEMBL28444819 | 0.73 | NPC1 (0.47) | CASRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1161604 | 0.72 | PIK3CD (0.50) | PIK3CDCASRELANEHTR1APARP1 | |
| SCHEMBL7016775 | 0.72 | ELANE (0.46) | PIK3CDCASRELANELMNAHSD17B10 | |
| SCHEMBL10173803 | 0.72 | PIK3CD (0.50) | PIK3CDCASRELANEHTR1APARP1 | |
| SCHEMBL9604076 | 0.70 | PIK3CD (0.76) | PIK3CDLMNAMAPTPDE4DHPGD | |
| SCHEMBL20404396 | 0.70 | PIK3CD (0.57) | PIK3CDLMNAMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111471023-A | Method for synthesizing quinazolinone compound under photocatalysis condition | 河南大学 | 2020-07-31 | — | — | CN | disclosed |