SCHEMBL28826602

SCHEMBL28826602

CN(C)C(c1ccncc1)C(N)c1ccncc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
CHRM5 P08912 1/20 0.38
CHKA P35790 1/20 0.38
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 2/20 0.35
SLC6A3 Q01959 2/20 0.35
MAPT P10636 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
ROCK2 O75116 2/20 0.33
ROCK1 Q13464 2/20 0.33
CYP19A1 P11511 1/20 0.33
DPP4 P27487 3/20 0.33
GAA P10253 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
CYP2D6 P10635 1/20 0.32
CHRM1 P11229 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6920106 0.78 DPP4 (0.56) CYP3A4SLC6A2SLC6A4SLC6A3DPP4
SCHEMBL6920099 0.78 DPP4 (0.56) CYP3A4SLC6A2SLC6A4SLC6A3DPP4
SCHEMBL6920104 0.78 DPP4 (0.56) CYP3A4SLC6A2SLC6A4SLC6A3DPP4
SCHEMBL16781699 0.77 DPP4 (0.50) CYP3A4CYP2C19SLC6A2SLC6A4SLC6A3
SCHEMBL5007561 0.73 CYP3A4 (0.44) CYP3A4CYP2C19SLC6A2SLC6A4SLC6A3
SCHEMBL2896524 0.73 CYP3A4 (0.44) CYP3A4CYP2C19SLC6A2SLC6A4SLC6A3
SCHEMBL417178 0.72
SCHEMBL2888206 0.72
SCHEMBL225809 0.72
Hydrochloric Acid SCHEMBL28802865 0.70 ROCK2 (0.53) CYP3A4CYP2C19SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108884030-B Improved labeling of nucleophiles using bipyridines 安捷伦科技有限公司 2022-06-28 CN disclosed