Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920106 | 1.00 | DPP4 (0.56) | DPP4AOC3F2KDM4EALDH1A1 | |
| SCHEMBL6920099 | 1.00 | DPP4 (0.56) | DPP4AOC3F2KDM4EALDH1A1 | |
| SCHEMBL5173218 | 0.85 | DPP4 (0.50) | DPP4AOC3F2KDM4EALDH1A1 | |
| SCHEMBL7586902 | 0.83 | HTR2A (0.52) | AOC3KDM4EALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL17571131 | 0.82 | AOC3 (0.53) | DPP4AOC3F2KDM4EALDH1A1 | |
| SCHEMBL19614378 | 0.82 | AOC3 (0.53) | DPP4AOC3F2KDM4EALDH1A1 | |
| SCHEMBL28826602 | 0.78 | CYP3A4 (0.39) | DPP4ALDH1A1SLC6A2SLC6A4CYP3A4 | |
| SCHEMBL26308183 | 0.78 | DPP4 (0.46) | DPP4AOC3F2KDM4ESLC6A2 | |
| SCHEMBL14350621 | 0.77 | KDM4E (0.57) | DPP4AOC3F2KDM4EALDH1A1 | |
| SCHEMBL29061569 | 0.77 | DPP4 (0.50) | DPP4AOC3F2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105680-A | Solid dispersion, method for preparing the same, chain-extended polyurethane using the same, and epoxy resin composition comprising the same | 株式会社三养社 | 2020-12-18 | — | — | CN | claimed |
| CN-120554243-A | Synthesis method of beta adamantyl amide compound | 南京工业大学 | 2025-08-29 | — | — | CN | disclosed |
| US-20250051434-A1 | MONOVALENT INTERLEUKIN 12 (IL-12) HETERODIMERIC FC PROTEINS | MERCK SHARP & DOHME LLC (US) | 2025-02-13 | — | — | US | disclosed |
| CN-118420500-A | Chiral organic catalyst and preparation method and application thereof | 苏州源锂新材料科技有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-112105680-A | Solid dispersion, method for preparing the same, chain-extended polyurethane using the same, and epoxy resin composition comprising the same | 株式会社三养社 | 2020-12-18 | — | — | CN | disclosed |
| WO-2019216700-A1 | SOLID DISPERSION, PREPARATION METHOD THEREFOR, CHAIN-EXTENDED POLYURETHANE USING SAME, AND EPOXY RESIN COMPOSITION COMPRISING SAME | 주식회사 삼양사 (KR) | 2019-11-14 | — | — | WO | disclosed |
| EP-2694466-B1 | PREPARATION OF SITAGLIPTIN INTERMEDIATES | LEK PHARMACEUTICALS (SI) | 2018-10-24 | — | — | EP | disclosed |
| CN-105802196-B | A kind of high molecular material and preparation method thereof with double process shape-memory effect | 中山大学 | 2018-08-07 | — | — | CN | disclosed |
| US-9174930-B2 | Preparation of sitagliptin intermediates | LEK PHARMACEUTICALS D.D. (SI) | 2015-11-03 | — | — | US | disclosed |
| US-20140213810-A1 | PREPARATION OF SITAGLIPTIN INTERMEDIATES | LEK PHARMACEUTICALS D.D. (SI) | 2014-07-31 | — | — | US | disclosed |
| EP-2623509-A1 | Method of producing an optically active amine compound by catalytic asymmetric hydrogenation using a ruthenium-diphosphine complex | Kanto Kagaku Kabushiki Kaisha (JP) | 2013-08-07 | — | — | EP | disclosed |
| US-20130197234-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE COMPOUND | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2013-08-01 | — | — | US | disclosed |
| CN-101225065-B | Chiral compound having multi-hydrogen bonds dual-function as well as synthetic method and use thereof | UNIV WUHAN | 2011-05-11 | — | — | CN | disclosed |
| CN-101225065-A | Chiral compound having multi-hydrogen bonds dual-function as well as synthetic method and use thereof | UNIV WUHAN (CN) | 2008-07-23 | — | — | CN | disclosed |
| WO-2004031168-A2 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF OPTICALLY ACTIVE 3-AMINO-1-(2-THIENYL)-1-PROPANOL DERIVATIVES | LONZA AG (CH) | 2004-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051434-A1 | MONOVALENT INTERLEUKIN 12 (IL-12) HETERODIMERIC FC PROTEINS | IL2RA, IL2, FCGR2A | DPP4 4806/4885AOC3 4731/4885F2 905/4885 |
| US-20130197234-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE COMPOUND | HRH3, TDO2, SRM | DPP4 3863/4885AOC3 523/4885F2 2592/4885 |
| US-20140213810-A1 | PREPARATION OF SITAGLIPTIN INTERMEDIATES | DPP4, DPP3, DPP9 | DPP4 1/4885AOC3 4321/4885F2 2536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.