Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28059756 | 0.74 | DRD4 (0.58) | DRD4KMT2AMAT2ADRD2 | |
| SCHEMBL28281701 | 0.70 | IDO1 (0.32) | — | |
| SCHEMBL28059853 | 0.69 | BCHE (0.49) | MGLLTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12528528 | 0.68 | GAA (0.52) | MGLLADRB1MEN1KMT2AALDH1A1 | |
| SCHEMBL27858734 | 0.64 | MGLL (0.41) | MGLLTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28396664 | 0.61 | ADRB1 (0.71) | ADRB1DRD4DRD2ALDH1A1ADRA1B | |
| SCHEMBL9626496 | 0.61 | MGLL (0.49) | MGLLNOTUMHCAR1MEN1KMT2A | |
| SCHEMBL11611482 | 0.61 | NOTUM (0.44) | MGLLNOTUMADRB1HCAR1MEN1 | |
| SCHEMBL27034876 | 0.61 | NOTUM (0.54) | NOTUMADRB1DRD4DRD2ALDH1A1 | |
| SCHEMBL15790773 | 0.60 | KCNN4 (0.47) | NOTUMHCAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104311553-B | Ortho position monochloro substituted compound and the synthetic method thereof of N-aryl azaindole | SHANGHAI UNIVERSITY (CN) | 2016-05-25 | — | — | CN | disclosed |