SCHEMBL28827166

SCHEMBL28827166

CC(C)(O)c1ccc(C(=O)c2ccc(Cl)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 2/20 0.55
MAPK1 P28482 2/20 0.55
POLB P06746 1/20 0.55
ELANE P08246 1/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
HPGD P15428 2/20 0.53
PPARG P37231 2/20 0.53
PPARA Q07869 2/20 0.53
FABP2 P12104 1/20 0.53
SLC22A12 Q96S37 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
CNR1 P21554 2/20 0.47
CNR2 P34972 1/20 0.47
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C19 P33261 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547765 0.89 SRD5A2 (0.59) SRD5A2ELANEHPGDSMN1; SMN2NPC1
SCHEMBL9395070 0.86 POLB (0.72) SRD5A2MAPK1POLBELANEMEN1
SCHEMBL1016971 0.85 KMT2A (0.71) MAPK1POLBMEN1KMT2ASMN1; SMN2
SCHEMBL8005246 0.82 SRD5A2 (0.53) SRD5A2MAPK1POLBELANEMEN1
SCHEMBL547672 0.82 ALDH1A1 (0.58) SRD5A2ELANEMEN1KMT2AHPGD
SCHEMBL7277668 0.82 MAPK1 (0.57) SRD5A2MAPK1POLBELANEMEN1
SCHEMBL10943769 0.80 MAPK1 (0.55) SRD5A2MAPK1POLBELANEMEN1
SCHEMBL548387 0.80 SRD5A2 (0.50) SRD5A2ELANEHPGDSMN1; SMN2NPC1
SCHEMBL9065412 0.80 SRD5A2 (0.80) SRD5A2MAPK1ELANEHPGDCNR1
SCHEMBL10697158 0.80 SRD5A2 (0.80) SRD5A2MAPK1ELANEHPGDCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105581989-A Pharmaceutical composition containing fenofibric acid CHANGCHUN FUCHUN PHARMACEUTICAL CO LTD 2016-05-18 CN disclosed