SCHEMBL28827366

SCHEMBL28827366

COCCS(=O)(=O)Cc1c[c]ccc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.37
POLB P06746 1/20 0.36
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 1/20 0.33
GLA P06280 1/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30
TLR7 Q9NYK1 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15939122 0.81 CYP2C19 (0.43) CYP2C19POLBKMT2AALDH1A1GLA
SCHEMBL26025885 0.80 POLB (0.47) CYP2C19POLBKMT2AALDH1A1GLA
SCHEMBL1167599 0.77 ENPP2 (0.35) CA1CA2CA9
SCHEMBL28129004 0.77 LOX (0.40) POLBKMT2AALDH1A1CA1CA2
SCHEMBL160785 0.76
SCHEMBL2642337 0.74 RCE1 (0.36) POLBKMT2AALDH1A1CA1CA2
SCHEMBL10710294 0.74 IDO1 (0.37) ALDH1A1MAPK1
SCHEMBL22912517 0.72 CYP2C19 (0.48) CYP2C19POLBKMT2AALDH1A1GLA
SCHEMBL23628 0.72 CYP2C19 (0.34) CYP2C19POLBALDH1A1CA1CA2
SCHEMBL15464302 0.72 MAOA (0.41) CYP2C19ALDH1A1CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105601627-A Heteroarylpiperidine and -piperazine derivatives as fungicides BAYER CROPSCIENCE AG 2016-05-25 CN disclosed