Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737452 | 0.80 | PTGS2 (0.40) | CA1CA2POLBMMP1MMP8 | |
| SCHEMBL1569729 | 0.79 | CA2 (0.59) | CA1CA2FAAHPRSS1PRSS2 | |
| SCHEMBL8910537 | 0.79 | CA1 (0.35) | CA1CA2FAAHPRSS1PRSS2 | |
| SCHEMBL239870 | 0.76 | RCE1 (0.35) | RCE1CA1CA2FAAHPRSS1 | |
| SCHEMBL28278790 | 0.75 | CA2 (0.58) | RCE1CA1CA2FAAHPRSS1 | |
| SCHEMBL92893 | 0.75 | CA2 (0.58) | RCE1CA1CA2FAAHPRSS1 | |
| SCHEMBL2574653 | 0.75 | POLB (0.46) | CA1CA2CA9POLBKMT2A | |
| SCHEMBL28827366 | 0.74 | CYP2C19 (0.37) | CA1CA2PRSS1PRSS2PRSS3 | |
| SCHEMBL27852503 | 0.73 | TSHR (0.39) | POLBKMT2ALMNAALDH1A1TSHR | |
| SCHEMBL58507 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108698992-A | 2- cyano isoindoline derivatives for treating cancer | 特殊治疗有限公司 | 2018-10-23 | — | — | CN | claimed |
| WO-2008086158-A1 | BENZODIHYDROQUINAZOLINE AS PI3 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-17 | — | — | WO | claimed |
| US-6211240-B1 | INSECTICIDES | NOVARTIS CORPORATION | 2001-04-03 | — | — | US | claimed |
| EP-0651737-B1 | O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES | CIBA GEIGY AG (CH) | 1998-07-29 | — | — | EP | claimed |
| EP-0777645-A1 | OXIME ETHERS AND THEIR USE AS PESTICIDES | Novartis AG (CH) | 1997-06-11 | — | — | EP | claimed |
| WO-1996006072-A1 | OXIME ETHERS AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1996-02-29 | — | — | WO | claimed |
| EP-0651737-A1 | O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES | Novartis AG (CH) | 1995-05-10 | — | — | EP | claimed |
| WO-1994026700-A1 | O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1994-11-24 | — | — | WO | claimed |
| US-10292973-B2 | Covalent irreversible inhibitors of USP7 as anti-cancer agents | PROGENRA, INC. (US) | 2019-05-21 | — | — | US | disclosed |
| CN-108698992-A | 2- cyano isoindoline derivatives for treating cancer | 特殊治疗有限公司 | 2018-10-23 | — | — | CN | disclosed |
| WO-2018160944-A1 | AZOLE COMPOUNDS AS UBIQUITIN-SPECIFIC PROTEASE USP7 INHIBITORS | PROGENRA, INC. (US) | 2018-09-07 | — | — | WO | disclosed |
| US-9717717-B1 | Methods of treating cancer through the inhibition of USP7 and immune system modulation | PROGENRA, INC. (US) | 2017-08-01 | — | — | US | disclosed |
| WO-2017023684-A2 | COVALENT IRREVERSIBLE INHIBITORS OF USP7 AS ANTI-CANCER AGENTS | PROGENRA, INC. (US) | 2017-02-09 | — | — | WO | disclosed |
| EP-1496052-B1 | NOVEL AMINOBENZAMIDE DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| WO-1997000859-A1 | THIOAMIDES S-OXIDES FOR USE AS PESTICIDES | NOVARTIS AG (CH) | 1997-01-09 | — | — | WO | disclosed |
| US-5583249-A | INSECTICIDES, MITICIDES, MICROBIOCIDES FOR PLANTS | CIBA-GEIGY CORPORATION (US) | 1996-12-10 | — | — | US | disclosed |
| WO-1996006072-A1 | OXIME ETHERS AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1996-02-29 | — | — | WO | disclosed |
| EP-0651737-A1 | O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES | Novartis AG (CH) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994026700-A1 | O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1994-11-24 | — | — | WO | disclosed |
| CN-1058778-A | INDOLE DERIVATIVES | GLAXO GROP LTD (GB) | 1992-02-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10292973-B2 | Covalent irreversible inhibitors of USP7 as anti-cancer agents | USP7, USP2, USP28 | RCE1 1039/4885CA1 2401/4885CA2 3297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.